The assessment criteria used to investigate these factors included image contrast, signal-to-noise ratio (SNR) and relative noise of the background (RNB). Materials and Methods: In this study, we used the SIMIND MC simulation code and Jaszczak phantom containing six spheres with different diameters placed into a water-filled cylindrical phantom for consideration of the effects of different factors on quality of the images obtained from Tc-99m SPECT imaging system. Aims and Objectives: The aim of this study is to investigate the effective factors in improvement of the SPECT image quality by using MC simulation. By using these codes, it is possible to set different imaging parameters and do various studies in the field of nuclear medicine imaging. Background: Monte Carlo (MC) simulation codes are used extensively for modeling the nuclear medicine imaging systems, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET).
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